The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Aliases： P2Y1
Entrez GeneID ： 5028
Swissprot： P47900
WB Predicted band size： 42kDa
Host/Isotype ： Mouse IgG2b
Species Reactivity： Human,Rat
Immunogen： Purified recombinant fragment of human P2RY1 (AA: extra mix) expressed in E. Coli.
