The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Aliases： HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
Entrez GeneID： 64805
Swissprot： Q9H244
WB Predicted band size ： 39.4kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human P2RY12 (AA: extra mix) expressed in E. Coli.
