The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Aliases: K2e; KRTE; CK-2e; KRT2A; KRT2E
Entrez GeneID: 3849
Swissprot: P35908
WB Predicted band size: 65.4kDa
Host/Isotype : Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human KRT2 (AA: 177-490) expressed in E. Coli.
