The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
Aliases： AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
Entrez GeneID： 7020
Swissprot： P05549
WB Predicted band size： 48kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human TFAP2A (AA: 1-100) expressed in E. Coli.
