The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Aliases: DJ1; DJ-1; GATD2; HEL-S-67p
Entrez GeneID : 11315
Swissprot: Q99497
WB Predicted band size: 19.8kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli.
