This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]
Aliases： HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80
Entrez GeneID： 10403
Swissprot ： O14777
WB Predicted band size： 74kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in Mammalian.
