This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
Aliases : HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80
Entrez GeneID : 10403
Swissprot: O14777
WB Predicted band size : 74KDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in mammalian cells.
