This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Aliases： BIE; EHK; K10; KPP; BCIE; CK10
Entrez GeneID： 3858
Swissprot ： P13645
WB Predicted band size ： 58.8kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human,Rat
Immunogen： Purified recombinant fragment of human KRT10 (AA: 146-455) expressed in E. Coli.
