Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
Aliases ： GUCA3; GC-SA3; GUC1A3; GUCSA3; GUCY1A1
Entrez GeneID ： 2982
Swissprot ： Q02108
WB Predicted band size ： 77.5kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.
