This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Aliases ： ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
Entrez GeneID： 4072
Swissprot： P16422
WB Predicted band size： 35kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human,Mouse,Rat
Immunogen： Purified recombinant fragment of human EPCAM (AA: 24-265) expressed in E. Coli.
