The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Aliases： IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha
Entrez GeneID： 3575
Swissprot： P16871
WB Predicted band size ： 51.6kDa
Host/Isotype： Mouse IgG2b
Species Reactivity ： Human
Immunogen： Purified recombinant fragment of human CD127 (AA: extra 21-239) expressed in E. Coli.
