This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Aliases： NECTIN3; PPR3; PRR3; PVRL3; PVRR3; CDW113; NECTIN-3
Entrez GeneID： 25945
Swissprot ： Q9NQS3
WB Predicted band size： 61kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human CD113 (AA: extra 282-404) expressed in E. Coli.
