This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Aliases: VCAM1; INCAM-100
Entrez GeneID: 7412
Swissprot : P19320
WB Predicted band size: 81.3kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human,Rat,Monkey
Immunogen: Purified recombinant fragment of human CD106 (AA: extra 25-183) expressed in E. Coli.
