This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
Aliases: ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
Entrez GeneID: 10850
Swissprot: Q9Y4X3
WB Predicted band size: 12.6kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human CCL27 (AA: 25-112) expressed in E. Coli.
