Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
Aliases： PRMT4; CARM1
Entrez GeneID： 10498
Swissprot ： Q86X55
WB Predicted band size： 65kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human,Mouse,Rat,Rabbit,Monkey
Immunogen ： Purified recombinant fragment of human CARM1 expressed in E. Coli.
