The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Aliases ： CANP; muCL; CANP1; SPG76; CANPL1; muCANP
Entrez GeneID： 823
Swissprot ： P07384
WB Predicted band size： 81.9kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human CAPN1 (AA: 501-714) expressed in E. Coli.
