This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
Aliases ： NIP3
Entrez GeneID ： 664
Swissprot ： Q12983
WB Predicted band size： 21.5kDa
Host/Isotype ： Mouse IgG2a
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human BNIP3 (AA: 50-155) expressed in E. Coli.
