The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
Aliases: ANON2; BULN2
Entrez GeneID : 627
Swissprot: P23560
WB Predicted band size: 27.8kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human BDNF (AA: 19-248) expressed in E. Coli.
