The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Aliases : ASP; APG5; APG5L; hAPG5; APG5-LIKE
Entrez GeneID : 9474
Swissprot : Q9H1Y0
WB Predicted band size : 32.4kDa
Host/Isotype : Mouse IgG2b
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.
