Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Aliases : APG4A; AUTL2
Entrez GeneID : 115201
Swissprot : Q8WYN0
WB Predicted band size : 45.4kDa
Host/Isotype : Mouse IgG2b
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human ATG4A (AA: 258-398) expressed in E. Coli.
