ApoO: apolipoprotein O, also known as MYO25, FAM121B, MGC4825. Entrez Protein NP_077027. It is a chrondroitin-sulfate chain containing member of the apolipoprotein family and is an original glycoprotein up-regulated by diabetes in human Heart. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.
Aliases MYO25; FAM121B; MGC4825
Entrez GeneID 79135
Swissprot Q9BUR5
WB Predicted band size 22.2kDa
Host/Isotype Mouse IgG1
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of ApoO expressed in E. Coli.
