APOL1(apolipoprotein L, 1), also known as APOL, APO-L, APOL-I. Entrez Protein NP_001130012. It is a 395aa secreted high density lipoprotein which binds to apolipoprotein A-I. And is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
Aliases APOL,APO-L, APOL- I
Entrez GeneID 8542
Swissprot O14791
WB Predicted band size 44kDa
Host/Isotype Mouse IgG1
Species Reactivity Human
Immunogen Purified recombinant fragment of APOL1 expressed in E. Coli.
