The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Aliases ： NR3C4; KD; AIS; SMAX1; HUMARA; AR
Entrez GeneID： 367
Swissprot ： P10275
WB Predicted band size ： 110kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human AR expressed in E. Coli.
