This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
Aliases DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP
Entrez GeneID 103
Swissprot P55265
WB Predicted band size 136kDa
Host/Isotype Mouse IgG1
Species Reactivity Human
Immunogen Purified recombinant fragment of human ADAR (AA: 1085-1223) expressed in E. Coli.
