This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
Aliases： CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
Entrez GeneID： 7412
Swissprot : P19320
WB Predicted band size： 81kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human VCAM1 expressed in E. Coli.
