The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
Aliases: P18; UBC9; C358B7.1
Entrez GeneID: 7329
Swissprot : P63279
WB Predicted band size: 18kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Monkey
Immunogen: Purified recombinant fragment of human UBE2I expressed in E. Coli.