This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Aliases: Tubulin beta-1 chain
Entrez GeneID: 81027
Swissprot: Q9H4B7
WB Predicted band size: 50.3kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse,Monkey,Rat
Immunogen: Purified recombinant fragment of human TUBB1 (AA: 33-166) expressed in E. Coli.
