This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Aliases： OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2
Entrez GeneID： 7205
Swissprot ： Q15654
WB Predicted band size： 50.3kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human TRIP6 (AA: 107-291) expressed in E. Coli.
