The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Aliases ： CD290
Entrez GeneID： 81793
Swissprot : Q9BXR5
WB Predicted band size： 94.6kDa
Host/Isotype： Mouse IgG2b
Species Reactivity ： Human
Immunogen： Purified recombinant fragment of human TLR10 (AA: extra(20-219)) expressed in E. Coli.
