The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Aliases： TIP; ESA1; PLIP; KAT5; cPLA2; HTATIP; ZC2HC5; HTATIP1
Entrez GeneID： 10524
Swissprot： Q92993
WB Predicted band size： 58.6kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human TIP60 (AA: 18-208) expressed in E. Coli.
