This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Aliases： BGCAN; betaglycan
Entrez GeneID： 7049
Swissprot： Q03167
WB Predicted band size： 93.4kDa
Host/Isotype： Mouse IgG2b
Species Reactivity： Human,Mouse
Immunogen： Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.
