TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Aliases： PSCTK4
Entrez GeneID： 7006
Swissprot： P42680
WB Predicted band size： 74kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human, Mouse
Immunogen： Purified recombinant fragment of TEC expressed in E. Coli.
