Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Aliases： E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3
Entrez GeneID： 6929
Swissprot： P15923
WB Predicted band size： 67.6kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human TCF3 expressed in E. Coli.
