This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Aliases : COR1; SCP3; SPGF4
Entrez GeneID: 50511
Swissprot: Q8IZU3
WB Predicted band size: 27.7kDa
Host/Isotype: Mouse IgG1
Species Reactivity Human
Immunogen: Purified recombinant fragment of human SYCP3 (AA: 27-128) expressed in E. Coli.
