This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Aliases： SLUG; WS2D; SLUGH1; SNAIL2
Entrez GeneID： 6591
Swissprot： O43623
WB Predicted band size： 30kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human SNAI2 (AA: 100-200) expressed in E. Coli.
