The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Aliases： ACT; AACT; GIG24; GIG25
Entrez GeneID： 12
Swissprot ： P01011
WB Predicted band size： 47.7kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human SERPINA3 (AA: 279-432) expressed in E. Coli.
