The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
Aliases: RAG-1; RNF74; MGC43321
Entrez GeneID: 5896
Swissprot: P15918
WB Predicted band size: 119kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.
