This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases： DARPP32; DARPP-32
Entrez GeneID： 84152
Swissprot： Q9UD71
WB Predicted band size： 23kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. Coli.
