This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
Aliases: BETA2; BHF-1; MODY6; NEUROD; bHLHa3
Entrez GeneID: 4760
Swissprot: Q13562
WB Predicted band size: 40kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human,Mouse,Monkey
Immunogen : Purified recombinant fragment of human Neurod (AA: 26-91 ) expressed in E. Coli.
