The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Aliases： CAS2; CASL; HEF1; CAS-L; CASS2
Entrez GeneID： 4739
Swissprot ： Q14511
WB Predicted band size ： 92.9kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human, Rat
Immunogen ： Purified recombinant fragment of human NEDD9 (AA: 82-398) expressed in E. Coli.
