The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Aliases : NCK; nck-1; NCKalpha
Entrez GeneID: 4690
Swissprot: P16333
WB Predicted band size : 47kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human,Monkey
Immunogen: Purified recombinant fragment of human NCK1 expressed in E. Coli.
