N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants.
Aliases: TE2; ARD1; NATD; ARD1A; ARD1P; OGDNS; DXS707; MCOPS1
Entrez GeneID: 8260
Swissprot: P41227
WB Predicted band size: 26.5kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human,Mouse,Monkey
Immunogen : Purified recombinant fragment of human NAA10 (AA: 111-235) expressed in E. Coli.
