This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases: NMYC; ODED; MODED; N-myc; bHLHe37
Entrez GeneID: 4613
Swissprot: P04198
WB Predicted band size: 49.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human MYCN (AA: 337-464) expressed in E. Coli.
