This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas.Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells.Tissue specificity: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Aliases： MSI1
Entrez GeneID: 4440
Swissprot: O43347
WB Predicted band size : 39kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human MSI1 expressed in E. Coli.
