IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Aliases ： Aldesleukin; TCGF; interleukin-2
Entrez GeneID ： 3558
Swissprot： P60568
WB Predicted band size： 17.6kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human,Mouse,Rat
Immunogen ： Purified recombinant fragment of IL2 expressed in E. Coli.
