This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Aliases: MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
Entrez GeneID: 51085
Swissprot: Q9NP71
WB Predicted band size: 93.1kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
