This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Aliases: MER; RP38; c-Eyk; c-mer; Tyro12
Entrez GeneID: 10461
Swissprot : Q12866
WB Predicted band size : 140-180 kDa
Host/Isotype: Mouse IgG2b
Species Reactivity: Human,Mouse
Immunogen: Purified recombinant fragment of human MERTK (AA:extra(21-220)) expressed in E. Coli.
