LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Aliases: TTG2; RBTN2; RHOM2; RBTNL1
Entrez GeneID : 4005
Swissprot: P25791
WB Predicted band size: 18.4kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
