This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region.
Aliases: HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
Entrez GeneID: 11026
Swissprot: Q8N6C8
WB Predicted band size: 47.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human LILRA3 (AA: 24-168) expressed in E. Coli.
