The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Aliases : K19; CK19; K1CS
Entrez GeneID: 3880
Swissprot: P08727
WB Predicted band size: 44.1kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human, Rat
Immunogen: Purified recombinant fragment of human KRT19 (AA: 80-400) expressed in E. Coli.
